KBI Biopharma, Inc. (KBI) said on Dec. 1 that it is establishing a new $150 million commercial manufacturing facility in Research Triangle Park (RTP).
The company said in a news release that it expects the 140,000-sq.-ft facility to be operational by the first quarter 2022. “KBI is co-investing in the facility with an undisclosed pharmaceutical partner to support manufacturing of their therapeutic protein programs, the statement said.
“KBI has helped to advance more than 300 molecules in more than 70 unique indications. By expanding our commercial manufacturing footprint with this facility, we are able to provide our partners with launch material and market supply”
“Expansion of our US-based cell culture operations is a key investment to support our clients’ commercialization strategies,” said KBI President and CEO Dirk Lange. “This state-of-the-art facility will leverage the latest innovation in automation and digitalization to best meet the needs for our clients.”
The new turn-key, design-build construction will utilize KBI’s proven single-use platform and provide supply reliability with redundant equipment, automation, and full utility backup, the statement says.The design enables flexibility to accommodate a variety of mammalian-based biologics manufacturing processes. It also includes a ring corridor for suite access and a “science on display” viewing corridor to showcase the facility to KBI partners.
The new RTP location will house up to six 2,000-liter, single-use bioreactor systems and associated harvest and purification equipment, which can produce more than 100 commercial batches annually. In tandem with the manufacturing operations, KBI will employ advanced analytical services for commercial product characterization and release testing capabilities to support commercial launch and routine supply.
The new site is located in close proximity to KBI’s RTP mammalian drug development labs in Patriot Park, a new multi-phase industrial park developed by Indianapolis-based Strategic Capital Partners. KBI collaborated closely with Cushman & Wakefield to secure this building near the Raleigh-Durham (RDU) International Airport.